Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132459 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL9811876 | 0.75 | GAA (0.54) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL12000927 | 0.74 | GAA (0.64) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL7177149 | 0.73 | MAPK1 (0.52) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL4178176 | 0.71 | MAPT (0.62) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL5806238 | 0.71 | MAPK1 (0.67) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL2372160 | 0.71 | MAPK1 (0.62) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL28590343 | 0.71 | PPARG (0.68) | ALDH1A1GAAPOLBSMN1; SMN2KMT2A | |
| SCHEMBL7317448 | 0.71 | GAA (0.59) | ALDH1A1GAAPOLBSMN1; SMN2TP53 | |
| SCHEMBL20750437 | 0.71 | POLB (0.64) | ALDH1A1GAAPOLBTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243173-A2 | New diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |