Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132459 | 0.83 | ALDH1A1 (0.58) | MAPK1CA1CA2CA9GAA | |
| SCHEMBL7348982 | 0.81 | GAA (0.49) | MAPK1CA1CA2CA9GAA | |
| SCHEMBL7348972 | 0.81 | GAA (0.49) | MAPK1CA1CA2CA9GAA | |
| SCHEMBL5099014 | 0.78 | NTSR1 (0.58) | GAAALDH1A1MAPTPOLBMMP2 | |
| SCHEMBL5098994 | 0.78 | NTSR1 (0.58) | GAAALDH1A1MAPTPOLBMMP2 | |
| SCHEMBL8742426 | 0.77 | CYP1A2 (0.51) | MAPK1GAAALDH1A1MAPTPOLB | |
| SCHEMBL8742422 | 0.77 | CYP1A2 (0.51) | MAPK1GAAALDH1A1MAPTPOLB | |
| SCHEMBL21037164 | 0.76 | MAPT (0.53) | GAAMAPTPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7657489 | 0.76 | GAA (0.52) | MAPK1CA1CA2CA9GAA | |
| SCHEMBL9811876 | 0.76 | GAA (0.54) | MAPK1CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-A2 | TREATMENT OF SEXUAL DYSFUNCTION | Warner-Lambert Company LLC (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002040008-A2 | TREATMENT OF SEXUAL DYSFUNCTION WITH NON PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | claimed |