Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 15/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622396 | 1.00 | BMP1 (0.45) | BMP1TAS2R14ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1077866 | 0.93 | BMP1 (0.50) | BMP1 | |
| SCHEMBL1078022 | 0.92 | BMP1 (0.46) | BMP1TAS2R14ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6685014 | 0.92 | BMP1 (0.46) | BMP1TAS2R14ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6679488 | 0.85 | BMP1 (0.43) | BMP1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1039183 | 0.85 | BMP1 (0.43) | BMP1NPSR1 | |
| SCHEMBL1077690 | 0.85 | BMP1 (0.43) | BMP1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1039459 | 0.85 | BMP1 (0.45) | BMP1NPSR1 | |
| SCHEMBL6622848 | 0.85 | BMP1 (0.45) | BMP1NPSR1 | |
| SCHEMBL1076810 | 0.84 | BMP1 (0.53) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |