Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776885 | 1.00 | LTA4H (0.57) | LTA4HMEN1KMT2AMAPTHPGD | |
| SCHEMBL25334353 | 0.93 | LTA4H (0.66) | LTA4HMEN1KMT2AMAPTHPGD | |
| SCHEMBL465891 | 0.93 | LTA4H (0.66) | LTA4HMEN1KMT2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL10950909 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| Bromide SCHEMBL10946982 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| Water SCHEMBL28456938 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL25433519 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| Water SCHEMBL6282450 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| Iodide SCHEMBL10947428 | 0.91 | LTA4H (0.64) | LTA4HMEN1KMT2AMAPTHPGD | |
| SCHEMBL10686193 | 0.88 | LTA4H (0.45) | LTA4HMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230985-A2 | Gamma-glutamyl-4-azoanilides, process for their preparation and their use for the determination of gamma-glutamyltransferase | Roche Diagnostics GmbH (DE) | 1987-08-05 | — | — | EP | disclosed |