Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | S100A9 | P06702 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952761 | 0.77 | PNMT (0.54) | IDO1CYP3A4HTR3EHTR3BHTR3A | |
| SCHEMBL4176549 | 0.74 | TSHR (0.42) | TSHRIDO1DBHL3MBTL1TP53 | |
| SCHEMBL3221871 | 0.74 | TSHR (0.42) | TSHRIDO1DBHL3MBTL1TP53 | |
| SCHEMBL2952783 | 0.74 | MIF (0.48) | IDO1MIF | |
| SCHEMBL502201 | 0.74 | KDM4E (0.48) | TSHRIDO1L3MBTL1TP53CYP3A4 | |
| SCHEMBL5537239 | 0.72 | ALDH1A1 (0.39) | TSHRTP53CYP3A4 | |
| SCHEMBL28709411 | 0.70 | MIF (0.52) | TSHRIDO1MIFDBHCYP3A4 | |
| SCHEMBL10821425 | 0.69 | PIK3CA (0.41) | TSHRCYP3A4DAOPNMT | |
| SCHEMBL7769505 | 0.69 | IDO1 (0.52) | TSHRIDO1DBHCYP3A4PNMT | |
| SCHEMBL5537375 | 0.68 | IDO1 (0.41) | IDO1MIFDBHDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244195-A1 | 2-Vinylpenams and process | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4560749-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4521598-A | 3-Azidocephalosporins | ELI LILLY AND COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| EP-0136177-A2 | 3-Azidocephalosporins as intermediates and novel antibacterial agents | ELI LILLY AND COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4259236-A | COLORFAST RED SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4101541-A | DYES FOR POLYESTERS OR POLYPROPYLENE | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-3998805-A | MONOAZO DYES; POLYESTERS; YELLOW, RED, OR ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |