Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778287 | 1.00 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL13430414 | 1.00 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL13430417 | 1.00 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL5473075 | 1.00 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL5473070 | 1.00 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL7774640 | 0.96 | HTR1A (0.50) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL9009836 | 0.96 | HTR1A (0.50) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL12128006 | 0.96 | HTR1A (0.50) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL2486046 | 0.96 | HTR1A (0.50) | GJB2TACR2HTR1ANT5EPDE4D | |
| SCHEMBL7774644 | 0.96 | HTR1A (0.50) | GJB2TACR2HTR1ANT5EPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103877-B1 | PHOSPHATE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |