Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053616 | 0.82 | EPHX2 (0.52) | PLA2G2ACA1CA9FAAHALDH1A1 | |
| SCHEMBL10952099 | 0.81 | LPAR1 (0.59) | KMT2AHPGDLPAR1LMNA | |
| SCHEMBL9509871 | 0.81 | CA12 (0.50) | CA1CA9CA12FAAHALDH1A1 | |
| SCHEMBL18531295 | 0.79 | CA12 (0.48) | CA1CA9CA12ALDH1A1MMP1 | |
| SCHEMBL6835933 | 0.79 | EPHX1 (0.48) | CA1CA9CA12ALDH1A1MMP1 | |
| SCHEMBL14855170 | 0.79 | EGLN1 (0.42) | PLA2G2ACA1CA9FAAHALDH1A1 | |
| SCHEMBL25227149 | 0.78 | EPHX1 (0.54) | CA1CA9CA12MMP1MMP2 | |
| SCHEMBL424525 | 0.78 | EPHX1 (0.54) | CA1CA9CA12KDM4EMMP1 | |
| SCHEMBL28610231 | 0.77 | CNR1 (0.41) | CA1CA9CA12FAAHMEN1 | |
| SCHEMBL10774313 | 0.77 | LPAR1 (0.61) | KMT2ALPAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |