Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868691 | 0.94 | FAAH (0.48) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL75710 | 0.91 | FAAH (0.50) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL9403702 | 0.91 | FAAH (0.50) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL965270 | 0.91 | CA12 (0.53) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL13778398 | 0.86 | CA12 (0.46) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL8951841 | 0.85 | FAAH (0.44) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL18531295 | 0.84 | CA12 (0.48) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL6835933 | 0.84 | EPHX1 (0.48) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL22574055 | 0.84 | CA12 (0.38) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL3966082 | 0.84 | MGLL (0.47) | CA12CA1CA9MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027537-C | Improvements in or relating to carbemate derivatives | LILLY CO ELI (US) | 1995-02-01 | — | — | CN | disclosed |
| EP-0296864-B1 | PROCESS FOR PREPARING UREAS | DOWELANCO (US) | 1993-09-15 | — | — | EP | disclosed |
| US-4987233-A | Process for preparing herbicidal ureas and insecticidal carbamates and carbamate derivatives | ELI LILLY AND COMPANY (US) | 1991-01-22 | — | — | US | disclosed |
| CN-1030233-A | The improved method of preparation carbamate derivatives | LILLY CO ELI (US) | 1989-01-11 | — | — | CN | disclosed |
| EP-0296864-A2 | Process for preparing ureas | DOWELANCO (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4268643-A | ENDCAPPING BY ETHERIFICATION OR ESTERIFICATION | SOCIETA ITALIANA RESINE S.I.R. S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |