SCHEMBL107785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5950465	0.91	MMP12 (0.44)	TRPV1ADRB2CA2HTR1A
	SCHEMBL3653415	0.88	ESR1 (0.55)	ESR1ESR2SLC6A2ADRA2AADORA3
	SCHEMBL7270279	0.87	ESR1 (0.62)	ESR1ESR2SLC6A2ADRA2AADORA3
	SCHEMBL1934439	0.86	ESR1 (0.52)	ESR1ESR2SLC6A2ADRA2AADORA3
	SCHEMBL108916	0.83	CYP1A2 (0.45)	DPP4TAAR1L3MBTL1TDP1CYP1A2
	SCHEMBL27547657	0.83	TAAR1 (0.45)	KDM4EPTGS1PTGS2TMEM97SIGMAR1
	(+)-Hannokinol SCHEMBL23229864	0.83	ESR1 (0.56)	ESR1ESR2SLC6A2ADRA2AALDH1A1
	(+)-Hannokinol SCHEMBL30361499	0.83	ESR1 (0.56)	ESR1ESR2SLC6A2ADRA2AALDH1A1
	(+)-Hannokinol SCHEMBL31237222	0.83	ESR1 (0.56)	ESR1ESR2SLC6A2ADRA2AALDH1A1
	SCHEMBL5505572	0.82	STAT3 (0.41)	ADRB3HSD17B10ADRB2ADRB1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.