Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500720 | 0.95 | STAT3 (0.40) | STAT3HTR1AADRB2CYP2C9HSD17B10 | |
| SCHEMBL8422662 | 0.85 | CYP1A2 (0.53) | STAT3CYP1A2 | |
| SCHEMBL9125921 | 0.83 | TYR (0.54) | ADRB2HSD17B10CYP1A2HCAR2ALOX5 | |
| SCHEMBL107785 | 0.82 | ESR1 (0.52) | HTR1AADRB2CYP2C9HSD17B10CYP1A2 | |
| SCHEMBL7478236 | 0.79 | CYP1A2 (0.41) | HSD17B10CYP1A2HCAR2ALOX5GRIN2D | |
| SCHEMBL7976757 | 0.79 | DRD2 (0.52) | — | |
| SCHEMBL2046459 | 0.78 | CNR1 (0.53) | HSD17B10CYP1A2HCAR2PTPN1ALOX5 | |
| SCHEMBL5950465 | 0.78 | MMP12 (0.44) | STAT3HTR1AADRB2 | |
| SCHEMBL29885834 | 0.76 | PTGS2 (0.45) | HTR1AHSD17B10PTPN1ALOX5ADRB3 | |
| SCHEMBL22419001 | 0.76 | PTGS2 (0.45) | HTR1AHSD17B10PTPN1ALOX5ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836151-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069153-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |