Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.74 |
| ▸ | HTR1D | P28221 | 5/20 | 0.68 |
| ▸ | HTR1B | P28222 | 5/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018529 | 0.90 | HTR1A (0.78) | HTR1AHTR1DHTR1BMPO | |
| SCHEMBL5471393 | 0.88 | HTR1A (0.70) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL14692901 | 0.87 | HTR1D (0.72) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL11290643 | 0.86 | HTR1A (0.72) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL12013054 | 0.84 | HTR1D (0.73) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL8299143 | 0.84 | HTR1A (0.77) | HTR1AHTR1DHTR1BMPO | |
| SCHEMBL5461625 | 0.83 | HTR1A (0.71) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL28267254 | 0.83 | HTR1A (0.66) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL8250982 | 0.82 | HTR1A (0.60) | HTR1AHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL8920992 | 0.82 | HTR1A (0.97) | HTR1AHTR1DHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |