Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 3/20 | 0.50 |
| ▸ | MC5R | P33032 | 2/20 | 0.50 |
| ▸ | MC3R | P41968 | 2/20 | 0.50 |
| ▸ | MC1R | Q01726 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | GNRHR | P30968 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779510 | 0.93 | C5AR1 (0.58) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL11101995 | 0.92 | C5AR1 (0.58) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL11392131 | 0.89 | C5AR1 (0.58) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL10784237 | 0.89 | C5AR1 (0.59) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL10784175 | 0.89 | C5AR1 (0.56) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL29391299 | 0.89 | C5AR1 (0.68) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL11103393 | 0.88 | C5AR1 (0.58) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL10784514 | 0.88 | NMUR2 (0.56) | C5AR1MC4R | |
| SCHEMBL11326066 | 0.88 | C5AR1 (0.59) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL11324467 | 0.87 | C5AR1 (0.53) | C5AR1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | disclosed |
| EP-0021234-B1 | NONAPEPTIDE AND DECAPEPTIDE DERIVATIVES OF LUTEINIZING HORMONE RELEASING HORMONE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1984-08-22 | — | — | EP | disclosed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | disclosed |
| EP-0021234-A1 | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1981-01-07 | — | — | EP | disclosed |