Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | GLP1R | P43220 | 2/20 | 0.49 |
| ▸ | MC4R | P32245 | 3/20 | 0.49 |
| ▸ | MC5R | P33032 | 2/20 | 0.49 |
| ▸ | MC3R | P41968 | 2/20 | 0.49 |
| ▸ | MC1R | Q01726 | 2/20 | 0.49 |
| ▸ | GNRHR | P30968 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103393 | 0.96 | C5AR1 (0.58) | C5AR1CXCR4KISS1RCTSLCTSS | |
| SCHEMBL11324467 | 0.96 | C5AR1 (0.53) | C5AR1MC4R | |
| SCHEMBL11326066 | 0.95 | C5AR1 (0.59) | C5AR1CXCR4PTGS1CTSLCTSS | |
| SCHEMBL11099915 | 0.94 | C5AR1 (0.62) | C5AR1CXCR4KISS1RPTGS1CTSL | |
| SCHEMBL10779510 | 0.93 | C5AR1 (0.58) | C5AR1CXCR4KISS1RPTGS1CTSL | |
| SCHEMBL10778825 | 0.92 | C5AR1 (0.58) | C5AR1CXCR4KISS1RPTGS1CTSL | |
| SCHEMBL11101417 | 0.91 | C5AR1 (0.59) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL10784237 | 0.89 | C5AR1 (0.59) | C5AR1CXCR4PTGS1CTSLCTSS | |
| SCHEMBL11392131 | 0.89 | C5AR1 (0.58) | C5AR1CXCR4KISS1RCTSLCTSS | |
| SCHEMBL10784175 | 0.88 | C5AR1 (0.56) | C5AR1CXCR4KISS1RCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042753-B1 | NONAPEPTIDE AND DECAPEPTIDE AGONISTS OF LUTEINIZING HORMONE RELEASING HORMONE CONTAINING HETEROCYCLIC AMINO ACID RESIDUES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM, AND THEIR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-03-21 | — | — | EP | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |