Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | MC5R | P33032 | 2/20 | 0.50 |
| ▸ | MC3R | P41968 | 2/20 | 0.50 |
| ▸ | MC1R | Q01726 | 2/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.48 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779510 | 0.95 | C5AR1 (0.58) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL11392131 | 0.95 | C5AR1 (0.58) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL10784237 | 0.90 | C5AR1 (0.59) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL9726210 | 0.90 | C5AR1 (0.59) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL10784514 | 0.90 | NMUR2 (0.56) | C5AR1MC4RNMUR2NMUR1 | |
| SCHEMBL10778825 | 0.89 | C5AR1 (0.58) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL11101995 | 0.88 | C5AR1 (0.58) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL11103393 | 0.88 | C5AR1 (0.58) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL9353686 | 0.86 | KISS1R (0.55) | C5AR1CXCR4KISS1RNMUR2NMUR1 | |
| Acetic Acid SCHEMBL29811007 | 0.86 | C5AR1 (0.64) | C5AR1CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | disclosed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | disclosed |