Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347640 | 0.90 | TSHR (0.44) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL10849734 | 0.88 | KCNA5 (0.36) | TSHRALDH1A1 | |
| SCHEMBL9857481 | 0.87 | F2 (0.38) | TSHRALDH1A1PIN1F2MEN1 | |
| SCHEMBL12787299 | 0.87 | TSHR (0.38) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL23529640 | 0.86 | TSHR (0.41) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL2915808 | 0.86 | TSHR (0.41) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL29772371 | 0.86 | TSHR (0.41) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL2915807 | 0.86 | TSHR (0.41) | TSHRALDH1A1PRNPPIN1F2 | |
| SCHEMBL10433826 | 0.86 | MAPT (0.36) | CYP3A4CYP2C19 | |
| SCHEMBL10562143 | 0.86 | MAPT (0.36) | CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244364-A2 | Preparation of olefinic compounds | SANDOZ AG (CH) | 1987-11-04 | — | — | EP | disclosed |