Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779090 | 0.87 | TSHR (0.39) | F2ALDH1A1TSHRF10MEN1 | |
| SCHEMBL9347640 | 0.87 | TSHR (0.44) | F2ALDH1A1TSHRF10SMN1; SMN2 | |
| SCHEMBL12787299 | 0.84 | TSHR (0.38) | F2ALDH1A1TSHRF10MEN1 | |
| SCHEMBL2915808 | 0.83 | TSHR (0.41) | F2ALDH1A1TSHRHTTMEN1 | |
| SCHEMBL29772371 | 0.83 | TSHR (0.41) | F2ALDH1A1TSHRF10SMN1; SMN2 | |
| SCHEMBL23529640 | 0.83 | TSHR (0.41) | F2ALDH1A1TSHRF10SMN1; SMN2 | |
| SCHEMBL2915807 | 0.83 | TSHR (0.41) | F2ALDH1A1TSHRHTTMEN1 | |
| SCHEMBL9857471 | 0.83 | PPID (0.41) | F2ALDH1A1F10KDM4ESMN1; SMN2 | |
| SCHEMBL9730290 | 0.83 | TSHR (0.38) | F2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9857466 | 0.83 | HSD11B1 (0.33) | F2ALDH1A1TSHRF10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436851-A1 | Compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1991-07-17 | — | — | EP | disclosed |