Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347640 | 0.89 | TSHR (0.44) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL10779090 | 0.87 | TSHR (0.39) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL2913428 | 0.87 | MMP12 (0.39) | TSHRNPC1 | |
| SCHEMBL2913434 | 0.87 | MMP12 (0.39) | TSHRNPC1 | |
| SCHEMBL23529640 | 0.85 | TSHR (0.41) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL29772371 | 0.85 | TSHR (0.41) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL2915807 | 0.85 | TSHR (0.41) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL2915808 | 0.85 | TSHR (0.41) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL9730290 | 0.85 | TSHR (0.38) | TSHRALDH1A1PIN1F2NPC1 | |
| SCHEMBL9857481 | 0.84 | F2 (0.38) | TSHRALDH1A1PIN1F2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | HMGCR, DPYD, FDPS | TSHR 4464/4885ALDH1A1 671/4885PIN1 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.