Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780894 | 1.00 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10778032 | 1.00 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10778036 | 1.00 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10774542 | 1.00 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6241100 | 0.92 | CA2 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10778924 | 0.92 | CA2 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5054302 | 0.86 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL21679654 | 0.86 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL21679674 | 0.86 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8917383 | 0.86 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |