Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433978 | 0.85 | HDAC3 (0.30) | — | |
| SCHEMBL21807143 | 0.85 | RAB9A (0.36) | MAPTTP53TSHRKDM4ELMNA | |
| SCHEMBL5630622 | 0.84 | CETP (0.40) | CETPMAPTTP53TOP2ALCK | |
| SCHEMBL7261886 | 0.79 | SLC6A3 (0.33) | PTPRCTSHRKDM4ELMNA | |
| SCHEMBL22389544 | 0.75 | — | — | |
| SCHEMBL29069277 | 0.75 | — | — | |
| SCHEMBL22389560 | 0.74 | — | — | |
| SCHEMBL22389524 | 0.74 | — | — | |
| SCHEMBL29069303 | 0.74 | — | — | |
| SCHEMBL11325697 | 0.74 | TYMS (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110396-B1 | IRON-TETRAPHENYLPORPHINE COMPLEX HAVING PHOSPHOCHOLINE GROUP AND OXYGEN ADSORBING AND DESORBING AGENT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |