Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781404 | 0.83 | MME (0.52) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL10778809 | 0.79 | BRD4 (0.50) | ALDH1A1HPGDKDM4EPOLBBDKRB1 | |
| SCHEMBL19116336 | 0.78 | CNR2 (0.53) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL12426304 | 0.77 | CNR2 (0.60) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL12991853 | 0.76 | BDKRB1 (0.57) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL4520630 | 0.75 | LMNA (0.57) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL10779369 | 0.74 | CNR2 (0.54) | CNR2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL10784392 | 0.74 | MAPK8 (0.49) | ALDH1A1HPGDKDM4EHTTTDP1 | |
| SCHEMBL10779521 | 0.74 | MEN1 (0.49) | ALDH1A1RAB9AKDM4EHTTTDP1 | |
| SCHEMBL20546008 | 0.74 | KDM4E (0.58) | CNR2ALDH1A1HPGDRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110484-B1 | DERIVATIVES OF AMINOPYRIDINECARBOXYLIC ACIDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Simes S.p.A. (IT) | 1987-09-02 | — | — | EP | disclosed |
| US-4528296-A | Derivatives of aminopyridinecarboxylic acids and pharmaceutical compositions containing them | SIMES, SOCIETA ITALIANA MEDICINALLE SINTETICI (IT) | 1985-07-09 | — | — | US | disclosed |
| EP-0110484-A1 | Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them | Simes S.p.A. (IT) | 1984-06-13 | — | — | EP | disclosed |