Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 12/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.45 |
| ▸ | HTR2C | P28335 | 11/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078087 | 0.85 | NOTUM (0.47) | NOTUMHTR2ASLC6A4HTR2C | |
| SCHEMBL1077551 | 0.84 | HTR2A (0.47) | NOTUMHTR2ASLC6A4HTR2CHCAR1 | |
| SCHEMBL1076424 | 0.81 | TSHR (0.51) | HTR2ASLC6A4HTR2C | |
| SCHEMBL16063426 | 0.80 | CNR1 (0.54) | MEN1KMT2A | |
| SCHEMBL30153810 | 0.75 | MAPT (0.49) | NOTUM | |
| SCHEMBL30387381 | 0.73 | WNT3A (0.64) | KMT2A | |
| SCHEMBL20604253 | 0.73 | WNT3A (0.64) | KMT2A | |
| SCHEMBL1079479 | 0.71 | PIK3R2 (0.51) | NOTUMHTR2ASLC6A4HTR2CMEN1 | |
| SCHEMBL16935876 | 0.70 | HCAR1 (0.47) | HCAR1 | |
| SCHEMBL16935859 | 0.70 | NOTUM (0.55) | NOTUMHTR2ASLC6A4HTR2CHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | claimed |
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |