Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784499 | 0.88 | HTT (0.33) | TSHRFFAR1PPARGPOLBAPEX1 | |
| SCHEMBL690484 | 0.83 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21980241 | 0.82 | HTT (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10779481 | 0.77 | POLB (0.40) | TSHRPPARGPOLBAPEX1HTT | |
| SCHEMBL10779755 | 0.76 | FFAR1 (0.34) | TSHRFFAR1PPARGAPEX1HTT | |
| SCHEMBL2289378 | 0.75 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9418250 | 0.74 | ELANE (0.36) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10603079 | 0.72 | POLB (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7907432 | 0.72 | AR (0.54) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3013436 | 0.71 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665217-A | DENTAL FILLERS AND COATINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |