Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957781 | 0.88 | AR (0.43) | HTTPOLBTDP1APEX1AR | |
| Propane SCHEMBL9476274 | 0.84 | HTT (0.53) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL59813 | 0.84 | POLB (0.56) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL14173142 | 0.84 | POLB (0.56) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL8957784 | 0.82 | HTT (0.45) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL17159501 | 0.82 | THRB (0.39) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL10779474 | 0.82 | TSHR (0.38) | HTTPOLBTDP1APEX1SMN1; SMN2 | |
| SCHEMBL3440176 | 0.81 | HTT (0.48) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL15257100 | 0.81 | HTT (0.46) | HTTPOLBTDP1APEX1AR | |
| SCHEMBL7907432 | 0.81 | AR (0.54) | HTTPOLBTDP1APEX1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3427715-B1 | DENTAL MATERIALS BASED ON LOW VISCOSITY RADICALLY POLYMERIZABLE MONOMERS HAVING A HIGH REFRACTIVE INDEX | IVOCLAR VIVADENT AG (LI) | 2021-03-03 | — | — | EP | claimed |
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | IVOCLAR VIVADENT AG (LI) | 2023-08-24 | — | — | US | disclosed |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | IVOCLAR VIVADENT AG (LI) | 2023-06-13 | — | — | US | disclosed |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | IVOCLAR VIVADENT AG (LI) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | MMAB, ALAD, SULT1E1 | HTT 439/4885POLB 1242/4885TDP1 2537/4885 |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | MMAB, ALAD, SULT1E1 | HTT 439/4885POLB 1242/4885TDP1 2537/4885 |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | MMAB, ALAD, SULT1E1 | HTT 439/4885POLB 1242/4885TDP1 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.