Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167472 | 0.83 | CYP3A4 (0.51) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL28687387 | 0.78 | PPARA (0.39) | FFAR1PPARGPPARASLC6A4SLC6A2 | |
| SCHEMBL6040933 | 0.78 | LTA4H (0.38) | PPARGPPARDPPARASLC6A4LMNA | |
| SCHEMBL10779474 | 0.76 | TSHR (0.38) | FFAR1PPARGPTPN5PPARDPPARA | |
| SCHEMBL196794 | 0.71 | KMT2A (0.37) | PPARGSLC6A4MEN1KMT2ASLC6A2 | |
| SCHEMBL10779364 | 0.71 | CYP3A4 (0.41) | PPARGPTPN5PPARASLC6A4MEN1 | |
| SCHEMBL9418699 | 0.71 | ALDH1A1 (0.49) | PPARASLC6A4MEN1KMT2ALMNA | |
| SCHEMBL7019539 | 0.68 | PPARD (0.46) | FFAR1PPARGPPARDPPARAAR | |
| SCHEMBL9394127 | 0.68 | PPARA (0.41) | FFAR1PPARGPPARDPPARACYP2D6 | |
| SCHEMBL29167511 | 0.68 | CYP3A4 (0.44) | SLC6A4MEN1KMT2ALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665217-A | DENTAL FILLERS AND COATINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |