Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780595 | 1.00 | MIF (0.50) | MIFGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10824149 | 1.00 | MIF (0.50) | MIFGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4898367 | 0.85 | KIF11 (0.47) | MIFGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4898359 | 0.85 | KIF11 (0.47) | MIFGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24885801 | 0.83 | LMNA (0.39) | MIFMAPTTSHRHTTHSD17B10 | |
| SCHEMBL30078241 | 0.83 | LMNA (0.39) | MIFMAPTTSHRHTTHSD17B10 | |
| SCHEMBL1931856 | 0.81 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29775672 | 0.81 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1931859 | 0.81 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2928249 | 0.81 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61033159-A | — | — | None | — | — | JP | disclosed |
| EP-0155792-B1 | BENZOATE DERIVATIVES HAVING POSITIVE DIELECTRIC ANISOTROPY AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4661283-A | Benzoate derivatives having a large positive dielectric anisotropy value and liquid crystal compositions containing same | CHISSO CORPORATION (JP) | 1987-04-28 | — | — | US | disclosed |
| JP-S6133159-A | CYANOPHENYL ESTER DERIVATIVE | CHISSO CORP | 1986-02-17 | — | — | JP | disclosed |
| EP-0155792-A1 | Benzoate derivatives having positive dielectric anisotropy and liquid crystal compositions containing them | Chisso Corporation (JP) | 1985-09-25 | — | — | EP | disclosed |