Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778614 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL14730825 | 0.85 | SMYD3 (0.57) | — | |
| SCHEMBL27854607 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL12858594 | 0.76 | TAS1R3 (0.51) | L3MBTL1ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL4735860 | 0.75 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ATSHRHPGD | |
| SCHEMBL4434322 | 0.74 | — | — | |
| SCHEMBL22372067 | 0.73 | TDP1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL1920569 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1TSHRCYP1A2 | |
| SCHEMBL12858668 | 0.72 | TDP1 (0.60) | ALDH1A1NPC1CYP1A2CYP2C19KDM4E | |
| SCHEMBL16182248 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126326-B1 | PROCESS FOR PREPARING 1,2,4-TRIAZOLE-3-CARBOXAMIDES | UBE INDUSTRIES, LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| US-4578479-A | Process for preparing 1,2,4-triazole-3-carboxamides | UBE INDUSTRIES, LTD. (JP) | 1986-03-25 | — | — | US | disclosed |
| EP-0126326-A1 | Process for preparing 1,2,4-triazole-3-carboxamides | UBE INDUSTRIES, LTD. (JP) | 1984-11-28 | — | — | EP | disclosed |