Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635089 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL28521563 | 0.82 | ALDH1A1 (0.95) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL27930239 | 0.79 | ALDH1A1 (0.79) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL11847292 | 0.78 | ALDH1A1 (0.78) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL1616513 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL11339777 | 0.77 | ALDH1A1 (0.75) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL29359563 | 0.77 | TSHR (1.00) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL1101208 | 0.77 | TSHR (1.00) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL146895 | 0.77 | TSHR (1.00) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL8957021 | 0.76 | ALDH1A1 (0.73) | ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150169-B1 | A PROCESS FOR PREPARING SUBSTITUTED BENZOTRICHLORIDE COMPOUNDS | Monsanto Company (US) | 1987-11-11 | — | — | EP | claimed |