Toluene

Toluene

SCHEMBL10782841

Cc1ccc(C(=O)c2ccc(C)cc2)cc1.Cc1ccccc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.80
LMNA P02545 3/20 0.80
SRD5A2 P31213 4/20 0.74
CES2 O00748 2/20 0.67
CES1 P23141 2/20 0.67
AKR1C3 P42330 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.61
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
TSHR P16473 1/20 0.55
ALOX12 P18054 1/20 0.55
ACHE P22303 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
HPGD P15428 1/20 0.54
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235 0.95 ALDH1A1 (0.80) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL10877169 0.95 ALDH1A1 (0.80) ALDH1A1LMNASRD5A2CES2CES1
Benzophenone SCHEMBL5162782 0.95 ALDH1A1 (0.80) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL259065 0.95 ALDH1A1 (0.80) ALDH1A1LMNASRD5A2CES2CES1
Hydrochloric Acid SCHEMBL4593809 0.93 ALDH1A1 (0.76) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL9500551 0.93 ALDH1A1 (0.76) ALDH1A1LMNASRD5A2CES2CES1
Bicarbonate SCHEMBL9817083 0.93 ALDH1A1 (0.76) ALDH1A1LMNASRD5A2CES2CES1
Hydrochloric Acid SCHEMBL4593815 0.93 ALDH1A1 (0.76) ALDH1A1LMNASRD5A2CES2CES1
Benzophenone SCHEMBL27484013 0.92 ALDH1A1 (0.74) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL822185 0.89 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170935-B1 THERMOTROPIC AROMATIC POLYESTERS HAVING A HIGH RIGIDITY, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND SHEETS BAYER AG (DE) 1987-11-25 EP disclosed
EP-0170935-A1 Thermotropic aromatic polyesters having a high rigidity, process for their preparation and their use in the production of moulded articles, filaments, fibres and sheets BAYER AG (DE) 1986-02-12 EP disclosed