Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.55 |
| ▸ | CES1 | P23141 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510642 | 0.74 | CES2 (0.46) | CES2CES1CA1CA2LMNA | |
| SCHEMBL21503691 | 0.74 | CES2 (0.59) | CES2CES1CA1CA2CA4 | |
| SCHEMBL9078831 | 0.74 | CES2 (0.59) | CES2CES1CA1CA2CA4 | |
| SCHEMBL8136241 | 0.72 | MEN1 (0.41) | LMNAMAPK1RAB9A | |
| SCHEMBL20705295 | 0.72 | CES2 (0.62) | CES2CES1CA1CA2CA4 | |
| SCHEMBL221480 | 0.72 | CES2 (0.67) | CES2CES1CA1CA2CA4 | |
| SCHEMBL10767862 | 0.71 | TDP1 (0.52) | CES2CES1CA1CA2CA4 | |
| SCHEMBL20702960 | 0.71 | CES2 (0.55) | CES2CES1CA1CA2CA4 | |
| SCHEMBL27989110 | 0.71 | CES2 (1.00) | CES2CES1CA1CA2CA4 | |
| SCHEMBL10925254 | 0.70 | TSHR (0.37) | CES2CES1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239992-A1 | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |