Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.48 |
| ▸ | CETP | P11597 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724158 | 0.85 | FAAH (0.56) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724597 | 0.85 | FAAH (0.56) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724576 | 0.85 | FAAH (0.56) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724599 | 0.83 | FAAH (0.54) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL7379778 | 0.83 | FAAH (0.59) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724577 | 0.83 | FAAH (0.54) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724159 | 0.83 | FAAH (0.54) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724578 | 0.83 | FAAH (0.53) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL8439259 | 0.83 | NMT1 (0.42) | MEN1KMT2AFAAHMAPK1DNM1 | |
| SCHEMBL21724603 | 0.82 | PLA2G2C (0.63) | MEN1KMT2AFAAHMAPK1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-RE32311-E | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| EP-0095295-A1 | Cyclic peptide derivatives | ELI LILLY AND COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |