SCHEMBL7379778

SCHEMBL7379778

CCCCCCCC(=O)N[C@H]([C]=O)CC(C)C

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPK1 P28482 1/20 0.59
PLA2G10 O15496 2/20 0.56
DNM1 Q05193 1/20 0.49
PSMB5 P28074 1/20 0.47
PLA2G2A P14555 2/20 0.47
PLA2G5 P39877 2/20 0.47
HSP90AA1 P07900 1/20 0.46
NOD1 Q9Y239 1/20 0.45
PLA2G2C Q5R387 1/20 0.45
ASAH2 Q9NR71 1/20 0.44
ALDH1A1 P00352 1/20 0.43
ASAH1 Q13510 1/20 0.43
ACER2 Q5QJU3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469992 0.93 FAAH (0.49) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL10783264 0.83 MEN1 (0.58) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL21724597 0.82 FAAH (0.56) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724158 0.82 FAAH (0.56) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724576 0.82 FAAH (0.56) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724577 0.81 FAAH (0.54) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724599 0.81 FAAH (0.54) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724159 0.81 FAAH (0.54) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL21724578 0.80 FAAH (0.53) FAAHMEN1KMT2AMAPK1PLA2G10
SCHEMBL10884800 0.80 FAAH (0.67) FAAHMEN1KMT2AMAPK1PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed