SCHEMBL10784104

SCHEMBL10784104

O=C(O)N(c1ccccc1)N(O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.46
ALDH1A1 P00352 4/20 0.41
NPC1 O15118 2/20 0.41
GLA P06280 2/20 0.41
HTT P42858 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PAX8 Q06710 1/20 0.41
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 2/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11136780 0.85 NPSR1 (0.55) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL8779740 0.76 NPSR1 (0.46) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL3056260 0.72 NPSR1 (0.52) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL27865747 0.71 ALDH1A1 (0.53) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL27342484 0.70 NPSR1 (0.50) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL28237283 0.70 NPSR1 (0.50) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL19778 0.69 NPSR1 (0.70) NPSR1ALDH1A1NPC1GLAHTT
SCHEMBL891832 0.69 NPSR1 (0.55) NPSR1ALDH1A1NPC1GLAHTT
Bromide SCHEMBL31210017 0.67 NPSR1 (0.67) NPSR1ALDH1A1NPC1GLAHTT
Hydrochloric Acid SCHEMBL5094831 0.67 NPSR1 (0.67) NPSR1ALDH1A1NPC1GLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104047-B1 MODIFIED OLIGOSACCHARIDES USED AS SUBSTRATE FOR MEASURING ALPHA-AMYLASE ACTIVITY WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1987-07-29 EP claimed