SCHEMBL28237283

SCHEMBL28237283

NC(=O)N(c1ccccc1)N(C(N)=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
POLB P06746 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C19 P33261 2/20 0.46
PARP1 P09874 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALOX5 P09917 1/20 0.42
KMT2A Q03164 3/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126163 0.86 RAB9A (0.44) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL15131370 0.80 NPSR1 (0.38) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL28148401 0.79 NPSR1 (0.64) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL75885 0.79 NPSR1 (0.64) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL764342 0.79 NPSR1 (0.50) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL75883 0.79 NPSR1 (0.64) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL11512637 0.78 NR3C2 (0.39) NPSR1ALDH1A1TSHRPOLBL3MBTL1
SCHEMBL11136780 0.78 NPSR1 (0.55) NPSR1ALDH1A1TSHRPOLBTDP1
Urea SCHEMBL23005263 0.77 NPSR1 (0.61) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL712279 0.77 NPSR1 (0.54) NPSR1ALDH1A1TSHRPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108469477-A A kind of assay method of Benzene in Beverages carbamide compound 厦门鉴科检测技术有限公司 2018-08-31 CN claimed
CN-108469477-A A kind of assay method of Benzene in Beverages carbamide compound 厦门鉴科检测技术有限公司 2018-08-31 CN disclosed