Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783302 | 0.99 | AKR1B1 (0.47) | AKR1B1MAPTAKR1B10AKR1A1ALDH1A1 | |
| SCHEMBL10783456 | 0.97 | AKR1B1 (0.47) | AKR1B1MAPTAKR1B10AKR1A1ALDH1A1 | |
| SCHEMBL10785899 | 0.87 | KDM4E (0.44) | MAPTALDH1A1GAA | |
| SCHEMBL10787723 | 0.86 | ALDH1A1 (0.41) | MAPTALDH1A1GAASIGMAR1 | |
| SCHEMBL10787913 | 0.85 | AKR1B1 (0.44) | AKR1B1MAPTAKR1B10AKR1A1 | |
| SCHEMBL10785195 | 0.85 | AKR1B1 (0.40) | AKR1B1SIGMAR1 | |
| SCHEMBL10788567 | 0.85 | SIGMAR1 (0.55) | AKR1B1MAPTAKR1B10AKR1A1SIGMAR1 | |
| SCHEMBL10784811 | 0.84 | KMT2A (0.41) | ALDH1A1GAASIGMAR1 | |
| SCHEMBL10785027 | 0.84 | AKR1B1 (0.40) | AKR1B1SIGMAR1 | |
| SCHEMBL10520213 | 0.84 | KMT2A (0.52) | MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650798-A | Antiarrhythmic 2,2-dialkyl-1-(aminoalkyl)-spiro[chroman-4,4'-imidazolidine]-2',5'-diones | EISAI CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |