SCHEMBL10784181

SCHEMBL10784181

CC(OS(=O)(=O)Cl)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
CYP1A2 P05177 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3441094 0.77 ALDH1A1 (0.50) TP53TSHRCYP1A2GAACYP2C9
SCHEMBL2781939 0.77 ALDH1A1 (0.50) TP53TSHRCYP1A2GAACYP2C9
SCHEMBL31149010 0.77 TP53 (0.36) TP53CYP1A2GAACYP2C9PKM
SCHEMBL28223681 0.77 TP53 (0.36) TP53CYP1A2GAACYP2C9PKM
SCHEMBL2329722 0.77 TP53 (0.36) TP53CYP1A2GAACYP2C9PKM
SCHEMBL4371933 0.77 ALDH1A1 (0.50) TP53TSHRCYP1A2GAACYP2C9
Ammonia Solution, Strong SCHEMBL1584317 0.75 TP53 (0.35) TP53CYP1A2GAACYP2C9PKM
SCHEMBL6909007 0.75 TP53 (0.35) TP53CYP1A2GAACYP2C9PKM
SCHEMBL11516838 0.75 TP53 (0.35) TP53CYP1A2GAACYP2C9PKM
SCHEMBL6910208 0.75 TP53 (0.35) TP53CYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4707549-A Preparation of esters of optically active 2-arylalkanoic acids BASF AKTIENGESELLSCHAFT (DE) 1987-11-17 US disclosed