Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441094 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TP53CYP1A2GAACYP2C9 | |
| SCHEMBL2781939 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TP53CYP1A2GAACYP2C9 | |
| Propene SCHEMBL27907290 | 0.89 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6451378 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KMT2ACA14 | |
| SCHEMBL28223681 | 0.79 | TP53 (0.36) | ALDH1A1TP53CYP1A2GAACYP2C9 | |
| SCHEMBL31149010 | 0.79 | TP53 (0.36) | ALDH1A1TP53CYP1A2GAACYP2C9 | |
| SCHEMBL2329722 | 0.79 | TP53 (0.36) | ALDH1A1TP53CYP1A2GAACYP2C9 | |
| SCHEMBL14339239 | 0.79 | ALDH1A1 (0.50) | ALDH1A1USP2TSHRCA1CA2 | |
| SCHEMBL17210383 | 0.77 | ALDH1A1 (0.48) | ALDH1A1USP2TSHR | |
| SCHEMBL16465564 | 0.77 | ALDH1A1 (0.48) | ALDH1A1USP2TSHRCA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167292-A1 | Process for preparing enantiomerically enriched 2-fluorocarboxylic esters | LANXESS DEUTSCHLAND GMBH (DE) | 2006-07-27 | — | — | US | claimed |
| CN-117957218-A | Targeted protein degradation using bifunctional compounds that bind to ubiquitin ligases and target MCL-1 proteins | 凯普托尔治疗学股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114127078-B | Heterocompounds and methods of use thereof | 重庆复创医药研究有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-111511728-B | Compound for separating rare earth elements and s, p, d metals, separation method and use thereof | 有机生物化学公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114127078-A | Hybrid compounds and methods of use thereof | 重庆复创医药研究有限公司 | 2022-03-01 | — | — | CN | disclosed |
| EP-3717466-B1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2022-01-05 | — | — | EP | disclosed |
| CN-109575022-B | Compound and application thereof | 成都海博锐药业有限公司 | 2021-09-21 | — | — | CN | disclosed |
| EP-3717466-A1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2020-10-07 | — | — | EP | disclosed |
| US-20200282331-A1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2020-09-10 | — | — | US | disclosed |
| CN-111511728-A | Compound for separating rare earth elements and s, p, d metals, separation method and use thereof | 有机生物化学公司 | 2020-08-07 | — | — | CN | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| US-5210258-A | Optically active alpha-naththylalkyl ketones | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1993-05-11 | — | — | US | disclosed |
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| US-H774-H | HERBICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| US-4912254-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICAL INTERNATIONAL LIMITED (BM) | 1990-03-27 | — | — | US | disclosed |
| EP-0081993-B1 | OPTICALLY ACTIVE ALPHA-SUBSTITUTED ARYL KETONES, THEIR PREPARATION AND THEIR USE IN PREPARING ALPHA-ARYLALKANOIC ACIDS | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1988-08-17 | — | — | EP | disclosed |
| US-4749804-A | Preparation of stereoisomers of ketals | SYNTEX (U.S.A.) INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4605758-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1986-08-12 | — | — | US | disclosed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167292-A1 | Process for preparing enantiomerically enriched 2-fluorocarboxylic esters | PHYKPL, PFAS, PFKFB2 | ALDH1A1 1500/4885TP53 4638/4885CYP1A2 404/4885 |
| US-20200282331-A1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | SCLY, SFXN1, PTCD3 | ALDH1A1 2634/4885TP53 2392/4885CYP1A2 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.