Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.80 |
| ▸ | ACHE | P22303 | 2/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | ESR1 | P03372 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.68 |
| ▸ | TNF | P01375 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802032 | 0.93 | PDE4A (0.88) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL7800864 | 0.92 | PDE4A (0.91) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL8362364 | 0.91 | RXFP1 (0.67) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL11347084 | 0.91 | PDE4A (0.89) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL11337820 | 0.91 | PDE4A (0.89) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL10788889 | 0.91 | PDE4A (0.89) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL11345748 | 0.91 | PDE4A (0.89) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL10784646 | 0.90 | PDE4A (0.84) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL9682866 | 0.90 | RXFP1 (0.77) | PDE4ALMNACYP1A2NFKB1ACHE | |
| Propentofylline SCHEMBL74602 | 0.89 | PDE4A (1.00) | PDE4ALMNACYP1A2NFKB1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121439-B1 | TRIS(DIALKYLAMINO)SULFONIUM BIFLUORIDE CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-25 | — | — | EP | claimed |
| US-4636507-A | Host defense mechanism enhancement | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-01-13 | — | — | US | claimed |
| EP-0121439-B1 | TRIS(DIALKYLAMINO)SULFONIUM BIFLUORIDE CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4598161-A | Tris(dialkylamino)sulfonium bifluoride catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0121439-A1 | Tris(dialkylamino)sulfonium bifluoride catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-10 | — | — | EP | disclosed |