Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871820 | 0.85 | TDP1 (0.57) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL27888075 | 0.84 | ALDH1A1 (0.56) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL6820186 | 0.83 | KDM4E (0.70) | TDP1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10784413 | 0.81 | TDP1 (0.60) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL10616390 | 0.79 | KDM4E (0.69) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31520212 | 0.76 | TSHR (0.67) | TDP1ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL11490448 | 0.76 | TSHR (0.67) | TDP1ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5162627 | 0.76 | ALDH1A1 (0.68) | TDP1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL28380448 | 0.74 | TDP1 (0.54) | TDP1GAAPOLBALDH1A1HPGD | |
| SCHEMBL11646433 | 0.74 | TDP1 (0.62) | TDP1GAAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141170-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| EP-0141170-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |