Styrene

Styrene

SCHEMBL10784459

C=CC(=C)c1ccccc1.C=Cc1ccccc1.C=Cc1ccccc1.C=Cc1ccccc1.C=Cc1ccccc1.C=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TSHR P16473 1/20 0.61
AKT1 P31749 1/20 0.45
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
AKR1C1 Q04828 1/20 0.36
PLIN1 O60240 1/20 0.36
LMNA P02545 1/20 0.36
BCHE P06276 1/20 0.36
MAPT P10636 1/20 0.36
TNFRSF1A P19438 1/20 0.36
ACHE P22303 1/20 0.36
MAOB P27338 1/20 0.36
RECQL P46063 1/20 0.36
PLIN5 Q00G26 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ABHD5 Q8WTS1 1/20 0.36
HDAC2 Q92769 1/20 0.36
CYP3A4 P08684 1/20 0.34
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10493188 1.00 ALDH1A1 (0.61) ALDH1A1TSHRAKT1TDP1TP53
Styrene SCHEMBL10534518 1.00 ALDH1A1 (0.61) ALDH1A1TSHRAKT1TDP1TP53
SCHEMBL108144 0.89 AKT1 (0.54) ALDH1A1TSHRAKT1TDP1LMNA
Butadiene SCHEMBL3389124 0.84 AKT1 (0.50) ALDH1A1TSHRAKT1TDP1LMNA
SCHEMBL8966417 0.84 ALDH1A1 (0.55) ALDH1A1TSHRAKT1TDP1TP53
Styrene SCHEMBL6443572 0.82 ALDH1A1 (0.67) ALDH1A1TSHRAKT1TDP1TP53
Bicarbonate SCHEMBL979087 0.82 AKT1 (0.60) ALDH1A1TSHRAKT1TDP1TP53
SCHEMBL12095541 0.81 TP53 (0.52) ALDH1A1TSHRAKT1TDP1TP53
Styrene SCHEMBL4259704 0.81 ALDH1A1 (0.93) ALDH1A1TSHRAKT1TDP1TP53
Styrene SCHEMBL2548841 0.80 ALDH1A1 (0.52) ALDH1A1TSHRAKT1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4658001-A STORAGE STABLE RANDOM COPOLYMERS WITH ANOTHER UNSATURATED COMPOUND NIPPON OILS & FATS CO., LTD. (JP) 1987-04-14 US disclosed