Styrene

Styrene

SCHEMBL2548841

C=CC=CC(=C)c1ccccc1.C=Cc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
MAPT P10636 3/20 0.36
RECQL P46063 3/20 0.36
MAOB P27338 2/20 0.36
PLIN1 O60240 2/20 0.36
LMNA P02545 2/20 0.36
PLIN5 Q00G26 2/20 0.36
ABHD5 Q8WTS1 2/20 0.36
BCHE P06276 1/20 0.36
TNFRSF1A P19438 1/20 0.36
ACHE P22303 1/20 0.36
CYP1B1 Q16678 1/20 0.36
AKT1 P31749 1/20 0.35
CYP3A4 P08684 2/20 0.34
HDAC2 Q92769 3/20 0.33
AKR1C1 Q04828 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HDAC3 O15379 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11269634 0.90 AKT1 (0.41) ALDH1A1TSHRMAPTRECQLMAOB
SCHEMBL2553036 0.90 AKT1 (0.41) ALDH1A1TSHRMAPTRECQLMAOB
SCHEMBL18522308 0.90 AKT1 (0.41) ALDH1A1TSHRMAPTRECQLMAOB
SCHEMBL27886109 0.82 AKT1 (0.39) ALDH1A1TSHRMAPTRECQLMAOB
Styrene SCHEMBL10784459 0.80 ALDH1A1 (0.61) ALDH1A1TSHRMAPTRECQLMAOB
Styrene SCHEMBL10493188 0.80 ALDH1A1 (0.61) ALDH1A1TSHRMAPTRECQLMAOB
Styrene SCHEMBL10534518 0.80 ALDH1A1 (0.61) ALDH1A1TSHRMAPTRECQLMAOB
Acrylonitrile SCHEMBL9464615 0.80 ALDH1A1 (0.35) ALDH1A1TSHRMAPTLMNAAKT1
Styrene SCHEMBL374493 0.79 ALDH1A1 (0.54) ALDH1A1TSHRMAPTRECQLMAOB
Styrene SCHEMBL1768760 0.79 ALDH1A1 (0.54) ALDH1A1TSHRMAPTRECQLMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141465-A1 PRELOADED INTRAOCULAR LENS INJECTOR AND METHOD OF USE THEREOF ICARES MEDICUS, INC. (TW) 2023-07-27 WO disclosed
EP-3691570-A1 INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF AST Products, Inc. (US) 2020-08-12 EP disclosed
EP-2932245-B1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2020-06-17 EP disclosed
US-10426602-B2 Intraocular lens (IOL) injector and method of use thereof AST PRODUCTS, INC. (US) 2019-10-01 US disclosed
US-10420640-B2 Detecting coatings on intraocular lens insertion devices and methods of manufacturing the devices Johnson & Johnson Surgical Vision, Inc. (US) 2019-09-24 US disclosed
WO-2019070282-A1 INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF AST PRODUCTS, INC. (US) 2019-04-11 WO disclosed
US-20190105151-A1 INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF AST PRODUCTS, INC. 2019-04-11 US disclosed
EP-3378443-A1 INTRAOCULAR LENS INSERTION DEVICE Abbott Medical Optics Inc. (US) 2018-09-26 EP disclosed
US-10022217-B2 Intraocular lens insertion device Johnson & Johnson Surgical Vision, Inc. (US) 2018-07-17 US disclosed
EP-2552352-B1 INTRAOCULAR LENS INSERTION DEVICE ABBOTT MEDICAL OPTICS INC (US) 2018-04-25 EP disclosed
US-20170128195-A1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES Johnson & Johnson Surgical Vision, Inc. 2017-05-11 US disclosed
US-20160081795-A1 INTRAOCULAR LENS INSERTION DEVICE Johnson & Johnson Surgical Vision, Inc. 2016-03-24 US disclosed
US-9198754-B2 Intraocular lens insertion device Abbott Medical Optics Inc. (US) 2015-12-01 US disclosed
EP-2932245-A1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES Abbott Medical Optics Inc. (US) 2015-10-21 EP disclosed
US-20140188122-A1 INTRAOCULAR LENS INSERTION DEVICE Johnson & Johnson Surgical Vision, Inc. 2014-07-03 US disclosed
WO-2014100013-A1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES Abbott Medical Optics Inc. (US) 2014-06-26 WO disclosed
US-20140171956-A1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES Abbott Medical Optics Inc. (US) 2014-06-19 US disclosed
US-8696682-B2 Intraocular lens insertion devices Abbott Medical Optics Inc. (US) 2014-04-15 US disclosed
EP-2552352-A2 INTRAOCULAR LENS INSERTION DEVICE Abbott Medical Optics Inc. (US) 2013-02-06 EP disclosed
WO-2011123315-A2 INTRAOCULAR LENS INSERTION DEVICE Abbott Medical Optics Inc. (US) 2011-10-06 WO disclosed