Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614317 | 0.91 | CA12 (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8602183 | 0.84 | CA12 (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12169294 | 0.84 | LMNA (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13508573 | 0.83 | CNR2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10282896 | 0.83 | TDP1 (0.49) | LMNAHTTSMN1; SMN2CA2VCAM1 | |
| SCHEMBL19563417 | 0.83 | SIGMAR1 (0.56) | LMNAHTTSMN1; SMN2VCAM1TDP1 | |
| SCHEMBL20245163 | 0.83 | KMT2A (0.54) | LMNASMN1; SMN2TDP1CNR2MAPT | |
| SCHEMBL20245336 | 0.83 | SIGMAR1 (0.56) | LMNAHTTSMN1; SMN2VCAM1TDP1 | |
| SCHEMBL5190090 | 0.82 | TDP1 (0.71) | LMNATDP1MAPTGAA | |
| SCHEMBL4589053 | 0.82 | CA12 (0.60) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085185-A1 | Integrated process for the preparation of substantially linear high molecular weight thermoplastic polymers from aryl polyhalide monomers | AMOCO CORPORATION (US) | 1983-08-10 | — | — | EP | claimed |
| EP-0085185-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY LINEAR HIGH MOLECULAR WEIGHT THERMOPLASTIC POLYMERS FROM ARYL POLYHALIDE MONOMERS | AMOCO CORPORATION (US) | 1987-05-20 | — | — | EP | disclosed |
| EP-0085185-A1 | Integrated process for the preparation of substantially linear high molecular weight thermoplastic polymers from aryl polyhalide monomers | AMOCO CORPORATION (US) | 1983-08-10 | — | — | EP | disclosed |