Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.67 |
| ▸ | CTSS | P25774 | 4/20 | 0.63 |
| ▸ | CTSL | P07711 | 3/20 | 0.63 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286173 | 0.86 | TAS1R3 (0.73) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25244468 | 0.86 | TAS1R3 (0.73) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL10780784 | 0.85 | TAS1R3 (0.69) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25238203 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25282469 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25517392 | 0.83 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL20853657 | 0.83 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25197064 | 0.83 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25287270 | 0.82 | TAS1R3 (0.70) | TAS1R3TAS1R1CTSSCTSLCTSK | |
| SCHEMBL25244832 | 0.82 | TAS1R3 (0.70) | TAS1R3TAS1R1CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099056-B1 | N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4610818-A | N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0099056-A2 | N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |