Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.70 |
| ▸ | CTSS | P25774 | 4/20 | 0.66 |
| ▸ | CTSL | P07711 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287270 | 1.00 | TAS1R3 (0.70) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL20853657 | 0.87 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25517392 | 0.87 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25197064 | 0.87 | TAS1R3 (0.78) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25244468 | 0.86 | TAS1R3 (0.73) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25286173 | 0.86 | TAS1R3 (0.73) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25288959 | 0.85 | TAS1R3 (0.66) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25288960 | 0.85 | TAS1R3 (0.66) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL6663347 | 0.83 | TAS1R3 (0.76) | TAS1R3TAS1R1CTSSCTSLGAA | |
| SCHEMBL25238203 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1CTSSCTSLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |