Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | CCR1 | P32246 | 6/20 | 0.61 |
| ▸ | CCR5 | P51681 | 6/20 | 0.61 |
| ▸ | CCR8 | P51685 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19268817 | 0.96 | KDM4E (0.64) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12817468 | 0.92 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 | |
| Phenanthroline SCHEMBL226209 | 0.92 | KDM4E (0.73) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29413987 | 0.90 | CCR1 (0.76) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL22101154 | 0.90 | CCR1 (0.76) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL17899316 | 0.90 | CCR1 (0.76) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL13929667 | 0.88 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL27064964 | 0.87 | CCR1 (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3748390 | 0.86 | KDM4E (0.72) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL22281848 | 0.86 | LMNA (0.46) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116037211-A | Cobalt-based complex catalyst and preparation method and application thereof | 合肥工业大学 | 2023-05-02 | — | — | CN | claimed |
| US-20120329767-A1 | Methods and Compositions for Treating Cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2012-12-27 | — | — | US | claimed |
| EP-2448588-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | Université de Strasbourg (FR) | 2012-05-09 | — | — | EP | claimed |
| WO-2011001109-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | UNIVERSITE DE STRASBOURG (FR) | 2011-01-06 | — | — | WO | claimed |
| EP-0623125-A1 | BRIDGED HETEROCYCLIC FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-09 | — | — | EP | claimed |
| WO-1993014080-A1 | BRIDGED HETEROCYCLIC FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| CN-1074443-A | The heterocyclic fungicides of bridging | DU PONT (US) | 1993-07-21 | — | — | CN | claimed |
| CN-116037211-A | Cobalt-based complex catalyst and preparation method and application thereof | 合肥工业大学 | 2023-05-02 | — | — | CN | disclosed |
| US-11316115-B2 | Organic compound, display panel and display device | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2022-04-26 | — | — | US | disclosed |
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2020-02-20 | — | — | US | disclosed |
| EP-3539971-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | Universidade de Santiago de Compostela (ES) | 2019-09-18 | — | — | EP | disclosed |
| US-20180019407-A1 | PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT | TORAY INDUSTRIES, INC (JP) | 2018-01-18 | — | — | US | disclosed |
| US-20180019407-A1 | PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT | TORAY INDUSTRIES, INC (JP) | 2018-01-18 | — | — | US | disclosed |
| US-20120329767-A1 | Methods and Compositions for Treating Cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120329767-A1 | Methods and Compositions for Treating Cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2012-12-27 | — | — | US | disclosed |
| EP-2448588-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | Université de Strasbourg (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001109-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | UNIVERSITE DE STRASBOURG (FR) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011001109-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | UNIVERSITE DE STRASBOURG (FR) | 2011-01-06 | — | — | WO | disclosed |
| EP-0623125-A1 | BRIDGED HETEROCYCLIC FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014080-A1 | BRIDGED HETEROCYCLIC FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019407-A1 | PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT | SUN2, PAH, FARS2 | KDM4E 488/4885LMNA 668/4885CCR1 4606/4885 |
| US-20120329767-A1 | Methods and Compositions for Treating Cancer | TP53, VHL, HCCS | KDM4E 2423/4885LMNA 1371/4885CCR1 1559/4885 |
| US-11316115-B2 | Organic compound, display panel and display device | DRD1, OXER1, C1S | KDM4E 3836/4885LMNA 3322/4885CCR1 143/4885 |
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | MYC, MYCBP, MCL1 | KDM4E 2445/4885LMNA 3613/4885CCR1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.