Phenanthroline

Phenanthroline

SCHEMBL226209

c1ccc(-c2ccccn2)nc1.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.73
LMNA P02545 7/20 0.73
CCR1 P32246 6/20 0.73
CCR5 P51681 6/20 0.73
CCR8 P51685 6/20 0.73
TP53 P04637 5/20 0.73
SMN1; SMN2 Q16637 5/20 0.73
HTT P42858 4/20 0.73
TDP1 Q9NUW8 4/20 0.73
MAPT P10636 4/20 0.73
ALOX15 P16050 3/20 0.73
HIF1A Q16665 2/20 0.73
HSP90AA1 P07900 2/20 0.73
MMP2 P08253 2/20 0.73
TSHR P16473 2/20 0.73
GMNN O75496 1/20 0.73
CYP3A4 P08684 1/20 0.73
CYP2D6 P10635 1/20 0.73
MMP9 P14780 1/20 0.73
NFKB1 P19838 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078553 0.92 KDM4E (0.61) KDM4ELMNACCR1CCR5CCR8
SCHEMBL19268817 0.89 KDM4E (0.64) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL28314262 0.88 KDM4E (0.61) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL22042790 0.86 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL29013283 0.85 CCR1 (0.89) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL29367277 0.85 CCR1 (1.00) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL29354015 0.85 CCR1 (1.00) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL8845760 0.85 CCR1 (1.00) KDM4ELMNACCR1CCR5CCR8
Phenanthroline SCHEMBL8312 0.85 CCR1 (1.00) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16512102 0.85 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661734-B Method for manufacturing circuit board and circuit board manufactured by the same 上村工业株式会社 2022-02-25 CN disclosed
US-20120003300-A1 Composition Comprising Vascular Endothelial Growth Factor (VEGF) for the Treatment of Hair Loss PANGAEA LABORATORIES LTD 2012-01-05 US disclosed
EP-1521753-A2 A PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL INTERMEDIATES. CADILA HEALTHCARE LTD. (IN) 2005-04-13 EP disclosed
WO-2004007490-A2 A PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL INTERMEDIATES. CADILA HEALTHCARE LIMITED (IN) 2004-01-22 WO disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
EP-0378407-B1 Electroless copper plating solution HITACHI CHEMICAL CO LTD (JP) 1994-03-23 EP disclosed
US-5086092-A Good paint adhesion BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0319792-B1 HEAT-CURABLE AQUEOUS COATING COMPOSITION FOR CATHODIC ELECTRODEPOSITION BASF Lacke + Farben AG (DE) 1992-01-22 EP disclosed