Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxybate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxybate SCHEMBL1124035 | 1.00 | CAMK2A (1.00) | — | |
| Oxybate SCHEMBL29059444 | 1.00 | CAMK2A (1.00) | — | |
| Oxybate SCHEMBL5566577 | 0.97 | — | — | |
| Oxybate SCHEMBL5668295 | 0.97 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL408934 | 0.97 | — | — | |
| Oxybate SCHEMBL23701412 | 0.97 | — | — | |
| Oxybate SCHEMBL18260136 | 0.97 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL18260134 | 0.97 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL20551245 | 0.97 | — | — | |
| Oxybate SCHEMBL5668354 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 129357 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410494-B1 | — | — | None | — | — | US | claimed |
| US-20260144768-A1 | MODIFIED RELEASE GAMMA-HYDROXYBUTYRATE FORMULATIONS HAVING IMPROVED PHARMACOKINETICS | FLAMEL IRELAND LIMITED (IE) | 2026-05-28 | — | — | US | claimed |
| EP-4747314-A1 | BIOPOLYMER BITUMEN SUBSTITUTE | Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO (NL) | 2026-05-27 | — | — | EP | claimed |
| CN-122075785-A | Reticular porous poly (3, 4-hydroxybutyrate) microsphere as well as preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12636476-B2 | Method of implantation of cell aggregates and tissue fragments | NEURONANO AB (SE) | 2026-05-26 | — | — | US | claimed |
| CN-122075721-A | Sustained release preparation of beta-hydroxybutyric acid or salt thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080323-A | Polyhydroxyalkanoate grafted ethylene-acrylic acid copolymer aqueous dispersion with self-emulsifying core-shell structure, preparation method and recyclable paper package thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-118267538-B | Oral cavity repairing film and preparation method thereof | Medprin Regenerative Medical Technologies Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121730120-B | PHA aqueous water-blocking coating pulp molding seedling raising basin containing inorganic filler and polymer blend and preparation method thereof | DBC NEW MATERIAL TECHNOLOGY (SHANGHAI) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122071872-A | Biopolymer coating composition for forming a multi-coating structure, and method for preparing a multi-coating structure | 新川创新股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-4138433-A | Process for preparing 1,2-oxa-phospholanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | claimed |
| US-4132778-A | INCREASING FEED-UTILIZATION EFFICIENCY IN RUMINANTS, BACTERICIDES, ANTIPROTOZOA, ANTICOCCIDIAL, INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | claimed |
| US-4107140-A | Production of the reaction products of oxidated silicon compounds reacting with organic monohydroxy compounds | BLOUNT DAVID H | 1978-08-15 | — | — | US | claimed |
| US-4073618-A | Anti-corrosive agent for metals | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-02-14 | — | — | US | claimed |
| US-4042666-A | Method of treating phosphate-containing material to reduce problem with clay swelling | PETROCHEMICALS COMPANY, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4038275-A | PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS | ELI LILLY AND COMPANY (US) | 1977-07-26 | — | — | US | claimed |
| US-3980428-A | ACID DYE, LACTONE | SANDOZ LTD. (CH) | 1976-09-14 | — | — | US | claimed |
| US-3963787-A | PALLADIUM CARBOXYLATE CATALYST | TEIJIN LIMITED (JA) | 1976-06-15 | — | — | US | claimed |
| US-3959003-A | Thixotropic cementing compositions | HALLIBURTON COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| US-3954581-A | HYDROXY CARBOXYLIC ACID AND PHOSPHONATE TO REDUCE HYDROGEN OVERVOLTAGE | PPG INDUSTRIES, INC. (US) | 1976-05-04 | — | — | US | claimed |