Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxybate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxybate SCHEMBL29059444 | 0.97 | CAMK2A (1.00) | — | |
| Oxybate SCHEMBL10786 | 0.97 | — | — | |
| Oxybate SCHEMBL1124035 | 0.97 | CAMK2A (1.00) | — | |
| Oxybate SCHEMBL5668295 | 0.93 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL408934 | 0.93 | — | — | |
| Oxybate SCHEMBL23701412 | 0.93 | — | — | |
| Oxybate SCHEMBL18260134 | 0.93 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL18260136 | 0.93 | CAMK2A (0.93) | — | |
| Oxybate SCHEMBL20551245 | 0.93 | — | — | |
| Oxybate SCHEMBL5668354 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051261-A | Drug delivery form such as tablets or pills made from a polymer and active ingredient | FMC CORPORATION (US) | 1991-09-24 | — | — | US | claimed |
| EP-1699855-B1 | PROCESS FOR PRODUCING A NANO-POROUS POLYMERIC MATERIAL, A POLYMER COMPOSITION COMPRISING NANOPARTICLES OF A CHEMICAL BLOWING AGENT, NANOPARTICLES OF A CHEMICAL BLOWING AGENT AND A NANO-POROUS POLYMERIC MATERIAL | DSM IP ASSETS BV (NL) | 2007-10-31 | — | — | EP | disclosed |
| EP-1699855-A1 | PROCESS FOR PRODUCING A NANO-POROUS POLYMERIC MATERIAL, A POLYMER COMPOSITION COMPRISING NANOPARTICLES OF A CHEMICAL BLOWING AGENT, NANOPARTICLES OF A CHEMICAL BLOWING AGENT AND A NANO-POROUS POLYMERIC MATERIAL | DSMIP Assets B.V. (NL) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005059015-A1 | PROCESS FOR PRODUCING A NANO-POROUS POLYMERIC MATERIAL, A POLYMER COMPOSITION COMPRISING NANOPARTICLES OF A CHEMICAL BLOWING AGENT, NANOPARTICLES OF A CHEMICAL BLOWING AGENT AND A NANO-POROUS POLYMERIC MATERIAL | DSM IP ASSETS B.V. (NL) | 2005-06-30 | — | — | WO | disclosed |
| EP-1541620-A1 | Process for producing a nano-porous polymeric material, a polymer composition comprising nanoparticles of a chemical blowing agent, nanoparticles of a chemical blowing agent and a nano-porous polymeric material | DSM IP Assets B.V. (NL) | 2005-06-15 | — | — | EP | disclosed |
| US-6207217-B1 | COMPRISING A METABOLIZABLE POLYHYDROXYALKLANOATE IN AN AMOUNT EFFECTIVE TO INCREASE THE ENERGY CONTENT OF ANIMAL FEED COMPOSITION | PIONEER HI-BRED INTERNATIONAL, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-0688865-A1 | Nucleotide sequence encoding acetoacetyl-CoA reductase and a method for producing polyester biopolymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-12-27 | — | — | EP | disclosed |