Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787486 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL10786109 | 0.87 | TSHR (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2FFAR3 | |
| SCHEMBL9691408 | 0.85 | CYP1A2 (0.51) | MAPTCACNA1CTSHR | |
| SCHEMBL10782467 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL10784057 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL9691213 | 0.84 | TSHR (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2FFAR3 | |
| SCHEMBL10894624 | 0.81 | NR3C2 (0.54) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL9691156 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL10914451 | 0.79 | KDM4E (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 | |
| SCHEMBL10781710 | 0.79 | NR3C2 (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110073-B1 | PROCESS FOR THE PREPARATION OF TETRAHYDROPYRIDINES | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0110073-A1 | Process for the preparation of tetrahydropyridines | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |