Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786897 | 0.87 | ADORA3 (0.52) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL10786103 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL10787486 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL9689715 | 0.83 | ADORA3 (0.49) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL9691613 | 0.83 | ADORA3 (0.49) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL9691408 | 0.81 | CYP1A2 (0.51) | MAPTMEN1KMT2AADORA3CACNA1C | |
| SCHEMBL9689619 | 0.81 | ADORA3 (0.47) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL10891614 | 0.81 | ADORA3 (0.64) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL11203237 | 0.80 | CACNA1C (0.48) | ALDH1A1MAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10784057 | 0.79 | KDM4E (0.50) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110073-B1 | PROCESS FOR THE PREPARATION OF TETRAHYDROPYRIDINES | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0110073-A1 | Process for the preparation of tetrahydropyridines | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |