SCHEMBL10786182

SCHEMBL10786182

CCC(CO)CC(C)C.[MgH2]

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
ALDH1A1 P00352 2/20 0.44
TSHR P16473 4/20 0.42
CACNA2D1 P54289 2/20 0.33
CACNB3 P54284 1/20 0.33
CACNA1C Q13936 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CACNA2D2 Q9NY47 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12345302 0.97
SCHEMBL135878 0.97
SCHEMBL10927040 0.94 TRPA1 (0.47) TRPA1ALDH1A1TSHRCACNA2D1CACNB3
SCHEMBL3199611 0.85
SCHEMBL14302635 0.84 TRPA1 (0.44) TRPA1ALDH1A1TSHRTDP1LMNA
SCHEMBL17464871 0.82 TRPA1 (0.42) TRPA1ALDH1A1TSHRTDP1LMNA
SCHEMBL246160 0.82 ALDH1A1 (0.52) TRPA1ALDH1A1TSHRADRA1ATDP1
SCHEMBL15158732 0.82 TSHR (0.53) TRPA1ALDH1A1TSHRCACNA2D1CACNB3
SCHEMBL29322852 0.80 TRPA1 (0.41) TRPA1ALDH1A1TSHRTDP1LMNA
SCHEMBL21332953 0.79 ALDH1A1 (0.50) TRPA1ALDH1A1TSHRADRA1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4634786-A INTERMEDIATES FOR ZIEGLER CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1987-01-06 US disclosed